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成年患者的幕上胚胎性肿瘤：病例报告与文献综述

Supratentorial Embryonal Tumor in Adult Patient: Case Report and Literature Review.

作者信息

Muñoz Montoya Juan Esteban, Rodríguez Paula Santamaria, Duarte Mora Diana Paola, Benavidez Rojas Mónica Sofia, Cortes Jaramillo Elsa Jimena, Chacón Zambrano Leonardo Andrés

机构信息

Departament of Neurosurgery, Hospital Militar Central, Universidad Militar Nueva Granada, Bogotá, Colombia.

Departament of Medicine, Universidad del Rosario, Bogotá, Colombia.

出版信息

Asian J Neurosurg. 2020 Aug 28;15(3):733-736. doi: 10.4103/ajns.AJNS_19_20. eCollection 2020 Jul-Sep.

DOI:10.4103/ajns.AJNS_19_20
PMID:33145242
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7591189/
Abstract

Embryonal tumors are the new nomenclature of the primitive neuroectodermal tumors or PNET. Their supratentorial location and their manifestation in adult population are not very frequent. Embryonal tumors are conformed from undifferentiated neuroepithelial cells that have the ability to show differentiation to several cell lines. Next is presented a case from an adult male patient with a clinical headache pictures and convulsions. With imaging study that shows a meningeal enhancement with frontal lobe infiltration with histopathological study of embryonic tumor with areas of glial differentiation.

摘要

胚胎性肿瘤是原始神经外胚层肿瘤（PNET）的新命名。它们位于幕上，在成人中并不常见。胚胎性肿瘤由未分化的神经上皮细胞组成，这些细胞能够向多种细胞系分化。接下来介绍一例成年男性患者，其临床表现为头痛和抽搐。影像学检查显示脑膜强化伴额叶浸润，组织病理学检查为胚胎性肿瘤伴胶质分化区域。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0116/7591189/7442fe07ba14/AJNS-15-733-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0116/7591189/d786fb3a1df2/AJNS-15-733-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0116/7591189/5d7b148f0ca5/AJNS-15-733-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0116/7591189/8cf35b9a5f74/AJNS-15-733-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0116/7591189/7442fe07ba14/AJNS-15-733-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0116/7591189/d786fb3a1df2/AJNS-15-733-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0116/7591189/5d7b148f0ca5/AJNS-15-733-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0116/7591189/8cf35b9a5f74/AJNS-15-733-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0116/7591189/7442fe07ba14/AJNS-15-733-g004.jpg

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本文引用的文献

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A primitive neuroectodermal tumor in an adult: Case report of a unique location and MRI characteristics.一名成人的原始神经外胚层肿瘤：独特部位及MRI特征的病例报告
Medicine (Baltimore). 2018 Feb;97(7):e9933. doi: 10.1097/MD.0000000000009933.
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Disseminated Cerebrospinal Embryonal Tumor in the Adult.成人播散性脑脊髓胚胎性肿瘤
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The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary.2016 年世界卫生组织中枢神经系统肿瘤分类：概述。
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Treatment Outcome and Prognostic Molecular Markers of Supratentorial Primitive Neuroectodermal Tumors.幕上原始神经外胚层肿瘤的治疗结果及预后分子标志物
PLoS One. 2016 Apr 13;11(4):e0153443. doi: 10.1371/journal.pone.0153443. eCollection 2016.
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A supratentorial primitive neuroectodermal tumor presenting with intracranial hemorrhage in a 42-year-old man: a case report and review of the literature.一名42岁男性患者出现颅内出血的幕上原始神经外胚层肿瘤：病例报告及文献复习
J Med Case Rep. 2013 Mar 27;7:86. doi: 10.1186/1752-1947-7-86.
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RAD51 overexpression is a negative prognostic marker for colorectal adenocarcinoma.RAD51 过表达是结直肠腺癌的一个负预后标志物。
Int J Cancer. 2013 May 1;132(9):2118-26. doi: 10.1002/ijc.27907. Epub 2012 Nov 5.
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The incidence of medulloblastomas and primitive neurectodermal tumours in adults and children.成人大脑髓母细胞瘤和原始神经外胚层肿瘤的发病率。
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Markers of survival and metastatic potential in childhood CNS primitive neuro-ectodermal brain tumours: an integrative genomic analysis.儿童中枢神经系统原始神经外胚层脑肿瘤生存和转移潜能的标志物：综合基因组分析。
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A primary primitive neuroectodermal tumor of the central nervous system in a 51-year-old woman: a case report and literature review.51 岁女性中枢神经系统原始神经外胚层肿瘤 1 例报告及文献复习
Medicina (Kaunas). 2011;47(8):440-5. Epub 2011 Nov 18.
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Supratentorial PNET in a young child.儿童幕上原始神经外胚层肿瘤。
Indian J Pediatr. 2011 May;78(5):613-5. doi: 10.1007/s12098-010-0301-0. Epub 2011 Jan 7.