Hagley M T, Lopez-Candales A, Phillips K J, Daily B B, Kouchoukos N T
Division of Cardiology, Jewish Hospital at Washington University Medical Center, St. Louis, Missouri 63110, USA.
Ann Thorac Surg. 1995 Dec;60(6):1814-6. doi: 10.1016/0003-4975(95)00627-3.
Two patients with new mitral valve bioprostheses required implantation of Bio-Medicus centrifugal pumps (Bio-Medicus, Minneapolis, MN) for circulatory support and had evidence of prosthetic valve thrombosis 1 and 4 days later. Both patients died of thromboembolic complications despite surgical removal of the thrombus. Thrombosis is a rare early complication of bioprosthetic valves and in these cases was probably related to low transvalvular flow due to the use of circulatory assist devices. We discuss possible strategies for avoiding and managing this catastrophic complication.
两名植入新型二尖瓣生物瓣膜的患者需要植入Bio-Medicus离心泵（Bio-Medicus，明尼阿波利斯，明尼苏达州）以提供循环支持，1天和4天后出现人工瓣膜血栓形成的证据。尽管手术清除了血栓，但两名患者均死于血栓栓塞并发症。血栓形成是生物瓣膜罕见的早期并发症，在这些病例中可能与使用循环辅助装置导致的跨瓣膜血流过低有关。我们讨论了避免和处理这种灾难性并发症的可能策略。
