Blangero J
Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78228-0147, USA.
Genet Epidemiol. 1995;12(6):689-706. doi: 10.1002/gepi.1370120628.
The statistical genetic analyses of a simulated data set for Genetic Analysis Workshop 9 Problem 2 are summarized. A diverse set of methods are evaluated with regard to the success with which they were able to determine the mode of inheritance and locate the genes underlying an oligogenically determined disease and four related quantitative traits.
对遗传分析研讨会9问题2的模拟数据集进行了统计遗传分析总结。评估了一系列不同方法在确定遗传模式以及定位寡基因决定疾病和四个相关数量性状潜在基因方面的成功程度。