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具有定量相关性的常见寡基因性状的遗传分析:GAW9结果总结

Genetic analysis of a common oligogenic trait with quantitative correlates: summary of GAW9 results.

作者信息

Blangero J

机构信息

Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78228-0147, USA.

出版信息

Genet Epidemiol. 1995;12(6):689-706. doi: 10.1002/gepi.1370120628.

Abstract

The statistical genetic analyses of a simulated data set for Genetic Analysis Workshop 9 Problem 2 are summarized. A diverse set of methods are evaluated with regard to the success with which they were able to determine the mode of inheritance and locate the genes underlying an oligogenically determined disease and four related quantitative traits.

摘要

对遗传分析研讨会9问题2的模拟数据集进行了统计遗传分析总结。评估了一系列不同方法在确定遗传模式以及定位寡基因决定疾病和四个相关数量性状潜在基因方面的成功程度。

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