Affecteds-only linkage methods are not a panacea.
作者信息
Greenberg D A, Hodge S E, Vieland V J, Spence M A
出版信息
Am J Hum Genet. 1996 Apr;58(4):892-5.
Abstract
摘要
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本文引用的文献
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Genetic analysis of a common oligogenic trait with quantitative correlates: summary of GAW9 results.具有定量相关性的常见寡基因性状的遗传分析：GAW9结果总结
Genet Epidemiol. 1995;12(6):689-706. doi: 10.1002/gepi.1370120628.
2
Evaluation of screening strategies to detect an oligogenic disease.检测寡基因疾病的筛查策略评估
Genet Epidemiol. 1995;12(6):665-9. doi: 10.1002/gepi.1370120624.
3
TDT with covariates and genomic screens with mod scores: their behavior on simulated data.带有协变量的传递不平衡检验以及具有修正分数的基因组筛选：它们在模拟数据上的表现。
Genet Epidemiol. 1995;12(6):659-64. doi: 10.1002/gepi.1370120623.
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Mapping of genes predisposing to idiopathic generalized epilepsy.特发性全身性癫痫易感基因的定位
Hum Mol Genet. 1995 Jul;4(7):1201-7. doi: 10.1093/hmg/4.7.1201.
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Better data analysis through data exploration.通过数据探索实现更好的数据分析。
Am J Hum Genet. 1993 Sep;53(3):775-7.
6
Adequacy of single-locus approximations for linkage analyses of oligogenic traits: extension to multigenerational pedigree structures.寡基因性状连锁分析中单基因座近似法的充分性：扩展到多代系谱结构
Hum Hered. 1993 Nov-Dec;43(6):329-36. doi: 10.1159/000154155.
7
Two-locus models of disease: comparison of likelihood and nonparametric linkage methods.疾病的双基因座模型：似然法与非参数连锁法的比较
Am J Hum Genet. 1993 Oct;53(4):908-15.
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Linkage analysis in nuclear families. 2: Relationship between affected sib-pair tests and lod score analysis.核心家庭中的连锁分析。2：受累同胞对检验与对数优势计分分析之间的关系。
Hum Hered. 1994 Jan-Feb;44(1):44-51. doi: 10.1159/000154188.
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Chromosome 18 DNA markers and manic-depressive illness: evidence for a susceptibility gene.18号染色体DNA标记与躁郁症：存在易感性基因的证据。
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