一种常见寡基因疾病的定量风险因素分析
Analysis of quantitative risk factors for a common oligogenic disease.
作者信息
Goddard K A, Jarvik G P, Graham J, McNeney B, Hsu L, Siegmund K, Grosser S, Olson J, Wijsman E M
机构信息
Department of Biostatistics, University of Washington, Seattle 98195, USA.
出版信息
Genet Epidemiol. 1995;12(6):759-64. doi: 10.1002/gepi.1370120638.
PMID:8788005
Abstract
All three simulated loci influencing the quantitative variables Q1, Q2 and Q3 were successfully mapped by using a strategy of covariate adjustment and segregation analysis, coupled with association analyses and lod-score analyses.
摘要
通过使用协变量调整和分离分析策略，结合关联分析和对数似然比分数分析，成功定位了影响定量变量Q1、Q2和Q3的所有三个模拟基因座。
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