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热解质谱及其在生物技术中的应用。

Pyrolysis mass spectrometry and its applications in biotechnology.

作者信息

Goodacre R, Kell D B

机构信息

Institute of Biological Sciences, University of Wales, Aberystwyth, Dyfed, SY23 3DA, UK.

出版信息

Curr Opin Biotechnol. 1996 Feb 1;7(1):20-8. doi: 10.1016/s0958-1669(96)80090-5.

DOI:10.1016/s0958-1669(96)80090-5
PMID:8791308
Abstract

Pyrolysis mass spectrometry is a rapid and high-resolution method for the analysis of otherwise non-volatile material and has been widely applied for discriminating between closely related microbial strains. Recent advances in statistical and neural network methods based on supervised learning have now permitted exploitation of pyrolysis mass spectrometry in the quantitative analysis of many diverse samples of biotechnological interest; the technique may thus be regarded as an 'anything-sensor'.

摘要

热解质谱分析法是一种用于分析非挥发性物质的快速且高分辨率的方法,已被广泛应用于区分密切相关的微生物菌株。基于监督学习的统计和神经网络方法的最新进展,现已使得热解质谱分析法可用于对许多具有生物技术研究价值的多样样品进行定量分析;因此,该技术可被视为一种“万能传感器”。

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