麻醉药品成瘾者肝脏疾病的谱和病因
The spectrum and causes of liver diseases in narcotic addicts.
作者信息
Gelb A M, Mildvan D, Stenger R J
出版信息
Am J Gastroenterol. 1977 Apr;67(4):314-8.
Fifty charts of patients discharged with a diagnosis of liver disease from the acute care service of a hospital for the treatment of addiction were analyzed. Among 42 active heroin users or former heroin addicts maintained on methadone, 79% were heavy alcohol abusers. Seventeen cases of cirrhosis were encountered. All occurred in those abusing alcohol. Reversible liver disease was seen in both alcohol abusers and nonalcoholics. This study suggests that alcohol is a major factor in the development of irreversible liver disease in active heroin addicts and ex-addicts on methadone maintenance.
对一家治疗成瘾的医院急性护理服务中诊断为肝病出院的50例患者的病历进行了分析。在42名服用美沙酮的现役海洛因使用者或 former heroin addicts 中，79%是重度酗酒者。发现了17例肝硬化病例。所有病例均发生在酗酒者中。酗酒者和非酗酒者均出现了可逆性肝病。这项研究表明，酒精是现役海洛因成瘾者和接受美沙酮维持治疗的 former heroin addicts 中不可逆肝病发展的主要因素。 （注：“former heroin addicts”直译为“以前的海洛因成瘾者”，结合语境可意译为“曾经的海洛因成瘾者” ）
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