Robillard J E, Sessions C, Kennedey R L, Hamel-Robillard L, Smith F G
Am J Obstet Gynecol. 1977 Aug 1;128(7):727-34. doi: 10.1016/0002-9378(77)90712-8.
The maturation of the glomerular filtration rate (GFR) and the interrelationship between the GFR and the renal transport of sodium and chloride have been evaluated during the last trimester of gestation with the use of long-term experiments in fetal lambs. An increase in GFR (milliliters per minute) parallel to the increase in fetal body weight was demonstrated; however, no significant change was shown when the GFR (milliliters per minute per kilogram of fetal body weight) (1.141 +/- 0.079) was related to fetal body weight or gestational age. There was a constant increase in sodium and chloride reabsorption (microequivalents per minute) during the last third of gestation. This increase in sodium and chloride reabsorption was less than the increase in GFR (milliliters per minute) before 129 days but became higher than the rise of GFR (milliliters per minute) after 129 days of gestation.
利用对胎羊进行的长期实验，在妊娠晚期评估了肾小球滤过率（GFR）的成熟情况以及GFR与钠和氯的肾脏转运之间的相互关系。结果表明，GFR（每分钟毫升数）的增加与胎儿体重的增加平行；然而，当GFR（每分钟每千克胎儿体重毫升数）（1.141±0.079）与胎儿体重或胎龄相关时，未显示出显著变化。在妊娠最后三分之一期间，钠和氯的重吸收（每分钟微当量）持续增加。在妊娠129天之前，钠和氯重吸收的这种增加小于GFR（每分钟毫升数）的增加，但在妊娠129天之后，其高于GFR（每分钟毫升数）的升高。
