Naeye R L, Harkness W L, Utts J
Am J Obstet Gynecol. 1977 Aug 1;128(7):740-6. doi: 10.1016/0002-9378(77)90714-1.
Abruptio placentae caused 3.96 perinatal deaths per 1,000 births in a large prospective study. Intrapartum but not prepartum maternal hypertension was observed in the fatal cases. Decidual necrosis at the placental margin and large placental infarcts were the most characteristic placental abnormalities. The decidual necrosis was correlated with maternal cigarette smoking and low pregnancy weight gains in the abruption placentae cases. The fetuses and neonates who died had a pattern of growth retardation characteristic of antenatal undernutrition, indicating that poor maternal nutrition during pregnancy may have contributed to the genesis of the abruptio placentae.
在一项大型前瞻性研究中，胎盘早剥导致每1000例分娩中有3.96例围产期死亡。在致命病例中观察到产时而非产前的母亲高血压。胎盘边缘的蜕膜坏死和大面积胎盘梗死是最具特征性的胎盘异常。在胎盘早剥病例中，蜕膜坏死与母亲吸烟和孕期体重增加不足有关。死亡的胎儿和新生儿具有产前营养不良特征性的生长迟缓模式，这表明孕期母亲营养不佳可能促成了胎盘早剥的发生。
