Chin-Yee I, Bezchlibnyk-Butler K, Wong L
Department of Hematology, London Health Sciences Centre, Ontario.
Can J Psychiatry. 1996 Jun;41(5):280-4. doi: 10.1177/070674379604100504.
To report and review the use of cytokines for the treatment of clozapine-induced neutropenia.
Case report and review of literature.
Cytokines, granulocyte colony-stimulating factor (G-CSF) and granulocyte-macrophage colony-stimulating factor (GM-CSF), appear to shorten the duration of clozapine-induced neutropenia.
G-CSF or GM-CSF therapy should be considered in patients with profound neutropenia of prolonged duration (high-risk neutropenia).
报告并综述细胞因子用于治疗氯氮平所致中性粒细胞减少症的情况。
病例报告及文献综述。
细胞因子，即粒细胞集落刺激因子（G-CSF）和粒细胞巨噬细胞集落刺激因子（GM-CSF），似乎可缩短氯氮平所致中性粒细胞减少症的持续时间。
对于持续时间较长的严重中性粒细胞减少症（高危中性粒细胞减少症）患者，应考虑采用G-CSF或GM-CSF治疗。
