van Haelst A G, Zhao Q, van der Wielen F W, Govers H A, de Voogt P
Department of Environmental and Toxicological Chemistry, Amsterdam Research Institute for Substances in Ecosystems, University of Amsterdam, The Netherlands.
Ecotoxicol Environ Saf. 1996 Jun;34(1):35-42. doi: 10.1006/eesa.1996.0042.
Accurate duplicate bioconcentration factors were determined for tetrachlorobenzyltoluenes (TCBTs). This is the first study that quantifies bioconcentration factors for single TCBT isomers. A continuous flow uptake experiment was performed during 21 days with the zebra mussel (Dreissena polymorpha) as a test organism. Bioconcentration factors (BCFs) and rate constants were derived by an iterative integration method. With this method BCFs and rate constants can be derived from experimental data of a bio-concentration test, even if the concentration in the water is not constant and steady state has not been reached. Mean log BCF values of TCBTs ranged from 4.43 +/- 0.05 to 5.19 +/- 0.15 liter.kg-1 on a wet weight basis. The experimental log BCF values were compared with log BCF values of TCBTs, calculated according to linear and polynomial relationships between log BCF and log Kow.
测定了四氯苄基甲苯（TCBTs）准确的重复生物富集系数。这是第一项对单一TCBT异构体的生物富集系数进行量化的研究。以斑马贻贝（多形饰贝）作为受试生物，进行了为期21天的连续流动摄取实验。通过迭代积分法得出生物富集系数（BCFs）和速率常数。使用该方法，即使水中的浓度不稳定且未达到稳态，也可从生物富集试验的实验数据中得出BCFs和速率常数。以湿重计，TCBTs的平均对数BCF值范围为4.43±0.05至5.19±0.15升·千克⁻¹。将实验得到的对数BCF值与根据对数BCF和对数辛醇-水分配系数（log Kow）之间的线性和多项式关系计算得出的TCBTs对数BCF值进行了比较。
