分娩期及产褥期的组织多肽抗原

Tissue polypeptide antigen during parturition and puerperium.

作者信息

Bergant A, Kirchler H, Schröcksnadel H, Daxenbichler G

机构信息

Department of Obstetrics and Gynecology, University of Innsbruck, Austria.

出版信息

Gynecol Obstet Invest. 1996;41(4):237-9. doi: 10.1159/000292276.

DOI:10.1159/000292276

PMID:8793492

Abstract

The tumour and cytoskeleton protein tissue polypeptide antigen (TPA) was determined in maternal serum taken during the second stage of labour and on the 4th postpartum day. Pregnant women at term (weeks 38-42) served as a control group. TPA levels of women during parturition (median 169 U/l) were higher than those of the control group (median 108.5 U/l) and those of women on the 4th postpartum day (median 66.5 U/l); p < 0.0001 in each case. The correlation between duration of labour and TPA concentration was positive and significant (rs = 0.3; p = 0.03). A significant negative correlation was found between placental weight and maternal serum TPA levels during parturition (rs = -0.3; p = 0.03). The decline of TPA after delivery indicated a serum half-life for TPA of less than 4 days.

摘要

在分娩第二阶段及产后第4天采集的孕妇血清中测定肿瘤及细胞骨架蛋白组织多肽抗原（TPA）。足月孕妇（38 - 42周）作为对照组。分娩期间女性的TPA水平（中位数169 U/l）高于对照组（中位数108.5 U/l）及产后第4天女性的TPA水平（中位数66.5 U/l）；每种情况p < 0.0001。产程与TPA浓度之间呈正相关且具有显著性（rs = 0.3；p = 0.03）。分娩期间胎盘重量与孕妇血清TPA水平之间存在显著负相关（rs = -0.3；p = 0.03）。产后TPA的下降表明TPA的血清半衰期小于4天。