• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Allele detection and population study in Japanese using two STR loci (CYP19 and HUMTH01).

作者信息

Takahashi M, Kato Y, Miyakawa G, Kurosu A, Kamiyama S

机构信息

Department of Legal Medicine, Dokkyo University School of Medicine, Tochigi, Japan.

出版信息

Int J Legal Med. 1996;108(6):321-2. doi: 10.1007/BF02432129.

DOI:10.1007/BF02432129
PMID:8793642
Abstract

Allele fragments at two polymorphic short tandem repeat (STR) loci, CYP19 and HUMTH01, were simultaneously amplified in a sample of 200 unrelated Japanese individuals living in the Kanto area, including Tokyo. After electrophoresis in PAG, the new alleles 7, 10, 11, 12, and 13 were detected at the CYP19 locus in Japanese. HUMTH01 allele frequencies in Japanese differed greatly from those reported for Caucasians and Asians living in the US. The polymorphism information content (PIC) in Japanese was calculated as 0.46 for CYP19 and 0.66 for HUMTH01. The power of discrimination (PD) was 0.7 for CYP19 and 0.86 for HUMTH01, and the combined PD was calculated as 0.96. No significant deviations from Hardy-Weinberg equilibrium could be observed for these systems.

摘要

相似文献

1
Allele detection and population study in Japanese using two STR loci (CYP19 and HUMTH01).
Int J Legal Med. 1996;108(6):321-2. doi: 10.1007/BF02432129.
2
Population study of the STRs HUMTH01 (including a new variant) and HUMVWA31A in Catalonia (northeast Spain).
Int J Legal Med. 1996;108(6):318-20. doi: 10.1007/BF02432128.
3
Population study of the HUMTH01, HUMVWA31A, HUMF13A1, and HUMFES/FPS STR polymorphisms in the north of Portugal.葡萄牙北部人群中HUMTH01、HUMVWA31A、HUMF13A1和HUMFES/FPS短串联重复序列多态性的研究
J Forensic Sci. 1997 Jan;42(1):121-4.
4
Combined polymorphism associated with a 3-bp deletion in the 5'-flanking region of a tetrameric short tandem repeat at the CYP19 locus.与CYP19基因座上一个四聚体短串联重复序列5'-侧翼区域中一个3碱基缺失相关的联合多态性。
Nihon Hoigaku Zasshi. 1997 Jun;51(3):191-5.
5
Swiss population data and forensic efficiency values on 3 tetrameric short tandem repeat loci-HUMTH01, TPOX, and CSF1PO-derived using a STR multiplex system.利用短串联重复序列（STR）复合扩增系统得出的瑞士人群数据以及3个四聚体短串联重复序列基因座（HUMTH01、TPOX和CSF1PO）的法医鉴定效率值。
Int J Legal Med. 1995;107(5):246-9. doi: 10.1007/BF01245482.
6
Frequency of the three STR loci (TPOX, CSF1PO, THo1), in a Japanese population determined using a Gene Print STR multiplex kit.使用基因打印STR复合试剂盒测定的日本人群中三个STR基因座（TPOX、CSF1PO、THo1）的频率。
Nihon Hoigaku Zasshi. 1996 Jun;50(3):163-7.
7
Short tandem repeat polymorphism at the HUMCD4 and HUMF13B loci in a Croatian population.克罗地亚人群中HUMCD4和HUMF13B基因座的短串联重复多态性
Int J Legal Med. 1997;110(4):230-1. doi: 10.1007/s004140050074.
8
Polymorphism of short tandem repeat (STR) loci PLA2, D3S2459, D8S315 (kw38), CYP19, D3S1359, FGA, and D8S1132 in the Japanese and Chinese populations.
Tohoku J Exp Med. 1997 Dec;183(4):251-62. doi: 10.1620/tjem.183.251.
9
Analysis of the STR loci HUMF13A01, HUMFXIIIB, HUMLIPOL, HUMTH01, HUMTPOX and HUMVWFA31 in a Japanese population.
Int J Legal Med. 1996;109(1):34-6. doi: 10.1007/BF01369599.
10
PCR analysis of the short tandem repeat (STR) system HUMVWA31. Allele and genotype frequencies in an Italian population sample.
Int J Legal Med. 1995;107(4):171-3. doi: 10.1007/BF01428399.

本文引用的文献

1
Identification of the remains of the Romanov family by DNA analysis.通过DNA分析鉴定罗曼诺夫家族的遗骸。
Nat Genet. 1994 Feb;6(2):130-5. doi: 10.1038/ng0294-130.
2
Identification of repeat sequence heterogeneity at the polymorphic short tandem repeat locus HUMTH01[AATG]n and reassignment of alleles in population analysis by using a locus-specific allelic ladder.利用位点特异性等位基因分型标准物鉴定多态性短串联重复序列位点HUMTH01[AATG]n处的重复序列异质性并在群体分析中重新指定等位基因
Am J Hum Genet. 1993 Oct;53(4):953-8.
3
Different types of structural variation in STRs: HumFES/FPS, HumVWA and HumD21S11.
STRs中不同类型的结构变异：人源FES/FPS、人源VWA和人源D21S11。
Int J Legal Med. 1994;106(6):319-23. doi: 10.1007/BF01224779.
4
Locus ACTBP2 (SE33). Sequencing data reveal considerable polymorphism.
Int J Legal Med. 1994;106(5):262-7. doi: 10.1007/BF01225417.
5
Population data and forensic efficiency values for the STR systems HumVWA, HumMBP and HumFABP.
Int J Legal Med. 1994;106(4):183-9. doi: 10.1007/BF01371334.
6
Construction of a genetic linkage map in man using restriction fragment length polymorphisms.利用限制性片段长度多态性构建人类遗传连锁图谱。
Am J Hum Genet. 1980 May;32(3):314-31.
7
Structural analysis of the gene encoding human aromatase cytochrome P-450, the enzyme responsible for estrogen biosynthesis.编码人芳香化酶细胞色素P-450的基因的结构分析，该酶负责雌激素的生物合成。
J Biol Chem. 1989 Nov 15;264(32):19385-91.
8
Tetranucleotide repeat polymorphism at the human aromatase cytochrome P-450 gene (CYP19).人类芳香化酶细胞色素P-450基因（CYP19）的四核苷酸重复多态性
Nucleic Acids Res. 1991 Jan 11;19(1):195. doi: 10.1093/nar/19.1.195.
9
Genetic variation at five trimeric and tetrameric tandem repeat loci in four human population groups.四个人类群体中五个三聚体和四聚体串联重复序列位点的遗传变异。
Genomics. 1992 Feb;12(2):241-53. doi: 10.1016/0888-7543(92)90371-x.
10
Performing the exact test of Hardy-Weinberg proportion for multiple alleles.对多个等位基因进行哈迪-温伯格比例的精确检验。
Biometrics. 1992 Jun;48(2):361-72.