Ames J B, Tanaka T, Stryer L, Ikura M
Department of Neurobiology, Stanford University School of Medicine, Stanford, California 94305, USA.
Curr Opin Struct Biol. 1996 Aug;6(4):432-8. doi: 10.1016/s0959-440x(96)80106-0.
Myristoylated proteins transduce a diverse range of cellular signals. Recoverin is a myristoylated, calcium-binding protein in the retina that serves as a calcium sensor in vision. The recent elucidation of the structures of several forms of myristoylated and unmyristoylated recoverin provides insight into how calcium induces the binding of recoverin to membranes.
肉豆蔻酰化蛋白可转导多种细胞信号。恢复蛋白是视网膜中的一种肉豆蔻酰化钙结合蛋白，在视觉过程中作为钙传感器发挥作用。最近对几种肉豆蔻酰化和非肉豆蔻酰化恢复蛋白形式的结构解析，为钙如何诱导恢复蛋白与膜结合提供了见解。
