Suppr超能文献

通道比散射校正方法的蒙特卡罗评估。

A Monte Carlo evaluation of the channel ratio scatter correction method.

作者信息

Naudé H, van Aswegen A, Herbst C P, Lötter M G, Pretorius P H

机构信息

Biophysics Department, University of the Orange Free State, Bloemfontein, South Africa.

出版信息

Phys Med Biol. 1996 Jun;41(6):1059-66. doi: 10.1088/0031-9155/41/6/009.

Abstract

Several methods exist to eliminate the contribution of scattered photons during imaging. One of these, the channel ratio (CR) scatter correction technique, uses the change in the ratio of counts from two symmetrical adjacent energy windows straddling the energy photopeak. The accuracy of the results depends upon the assumption that the ratio of the scatter components in the two windows (H value) is constant and is independent of the relative size of the scatter contribution. In this study a Monte Carlo simulation was used to investigate the behaviour of the scatter component for different source sizes at different depths. Four disc sources containing a 99Tcm solution were simulated at different depths as imaged with a scintillation camera. Two 10% energy windows with 5% offsets to either side of the 140 keV photopeak of 99Tcm were used. The ratio of the scattered counts in the lower energy window to the scattered counts in the upper window (true H value) was determined from the simulation for each source at every depth. Since it is impossible to measure the true H value at different organ depths during a clinical study, the use of an average H value was considered. Scatter correction was applied to the images simulated at the various depths in water. The geometric mean was calculated and attenuation correction performed assuming mono-exponential attenuation. For quantitation purposes the corrected counts were expressed in terms of a references source. The choice of the reference source yielding the best quantitative results was also investigated. Results of this Monte Carlo simulation study show that although the true H value depends on both source size and depth of the source in the scattering medium, the CR scatter correction technique can be applied successfully when an average H value is used.

摘要

在成像过程中,有几种方法可用于消除散射光子的影响。其中一种方法,即通道比(CR)散射校正技术,利用跨越能量光电峰的两个对称相邻能量窗口的计数比变化。结果的准确性取决于这样一个假设,即两个窗口中的散射分量之比(H值)是恒定的,并且与散射贡献的相对大小无关。在本研究中,使用蒙特卡罗模拟来研究不同源尺寸在不同深度下散射分量的行为。模拟了四个含有99Tcm溶液的圆盘源在不同深度的情况,并用闪烁相机进行成像。使用了两个10%的能量窗口,分别位于99Tcm的140keV光电峰两侧各有5%的偏移。从模拟中确定每个源在每个深度下低能量窗口中的散射计数与高能量窗口中的散射计数之比(真实H值)。由于在临床研究中不可能在不同器官深度测量真实H值,因此考虑使用平均H值。对在水中不同深度模拟的图像应用散射校正。计算几何平均值,并假设单指数衰减进行衰减校正。为了进行定量,校正后的计数以参考源表示。还研究了产生最佳定量结果的参考源的选择。这项蒙特卡罗模拟研究的结果表明,尽管真实H值取决于源尺寸和源在散射介质中的深度,但当使用平均H值时,CR散射校正技术可以成功应用。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验