Dautzenberg B
Service de pneumologie Groupe hospitalier Pitié-Salpbtnère, Paris.
Rev Prat. 1996 Jun 1;46(11):1350-5.
The standard antituberculous treatment consists during the first 2 months of daily rifampin 10 mg/kg, isoniazid 4-5 mg/kg and pyrazinamide 25 mg/kg, with ethambutol 20 mg/kg in case of suspicion of drug resistance. The second phase of treatment consists of 4 months rifampin and isoniazid at the same daily dosage. Two or three drugs combination pills simplify the treatment. An early treatment and a good follow up are prognostic factors of individual success and tuberculosis epidemic reduction. In case of multidrug resistance, susceptibility tests should be obtained before new initiation of treatment.
标准抗结核治疗在最初2个月包括每日服用利福平10毫克/千克、异烟肼4 - 5毫克/千克和吡嗪酰胺25毫克/千克，若怀疑耐药则加用乙胺丁醇20毫克/千克。治疗的第二阶段包括4个月服用相同日剂量的利福平和异烟肼。两联或三联复方制剂简化了治疗。早期治疗和良好的随访是个体治疗成功及减少结核病流行的预后因素。对于耐多药情况，在重新开始治疗前应进行药敏试验。
