吸烟对埃及血吸虫病患者谷胱甘肽-S-转移酶M1缺乏相关的膀胱癌鳞状细胞癌风险的影响。
Influence of smoking in the glutathione-S-transferase M1 deficiency--associated risk for squamous cell carcinoma of the bladder in schistosomiasis patients in Egypt.
作者信息
Lafuente A, Zakahary M M, el-Aziz M A, Ascaso C, Lafuente M J, Trias M, Carretero P
机构信息
Institut de Salut Pública, University of Barcelona, Spain.
出版信息
Br J Cancer. 1996 Sep;74(5):836-8. doi: 10.1038/bjc.1996.445.
Abstract
In this study we show an effect of the glutathione-S-transferase M1 (GSTM1) null phenotype on the risk for squamous cell carcinoma (SCC) of the bladder among male smokers in Egypt, with an adjusted odds ratio of 4.8 (95% confidence interval: 1.06-21.77). However, no overall effect of the GSTM1 null phenotype on the risk for bladder SCC was observed.
摘要
在本研究中，我们发现谷胱甘肽-S-转移酶M1（GSTM1）基因缺失型对埃及男性吸烟者患膀胱鳞状细胞癌（SCC）的风险有影响，校正比值比为4.8（95%置信区间：1.06-21.77）。然而，未观察到GSTM1基因缺失型对膀胱SCC风险的总体影响。
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本文引用的文献
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Cancer Lett. 1993 Jan 15;68(1):49-54. doi: 10.1016/0304-3835(93)90218-x.
3
Relationship between the GSTM1 genetic polymorphism and susceptibility to bladder, breast and colon cancer.谷胱甘肽S-转移酶M1（GSTM1）基因多态性与膀胱癌、乳腺癌和结肠癌易感性之间的关系。
Carcinogenesis. 1993 Sep;14(9):1821-4. doi: 10.1093/carcin/14.9.1821.
4
Homozygous deletion of gene for glutathione S-transferase M1 in bladder cancer.膀胱癌中谷胱甘肽S-转移酶M1基因的纯合缺失
BMJ. 1993 Aug 21;307(6902):481-2. doi: 10.1136/bmj.307.6902.481.
5
Influence of cigarette smoking and schistosomiasis on p53 gene mutation in urothelial cancer.吸烟与血吸虫病对尿路上皮癌中p53基因突变的影响。
Cancer Res. 1993 Aug 15;53(16):3795-9.
6
Genetic risk and carcinogen exposure: a common inherited defect of the carcinogen-metabolism gene glutathione S-transferase M1 (GSTM1) that increases susceptibility to bladder cancer.遗传风险与致癌物暴露：致癌物代谢基因谷胱甘肽S-转移酶M1（GSTM1）的一种常见遗传缺陷，会增加患膀胱癌的易感性。
J Natl Cancer Inst. 1993 Jul 21;85(14):1159-64. doi: 10.1093/jnci/85.14.1159.
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