Suppr超能文献

缝合巩膜瓣可使低眼压性黄斑病变得到缓解。

Resuturing the scleral flap leads to resolution of hypotony maculopathy.

作者信息

Schwartz G F, Robin A L, Wilson R P, Suan E P, Pheasant T R, Prensky J G

机构信息

Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USA.

出版信息

J Glaucoma. 1996 Aug;5(4):246-51.

PMID:8795769
Abstract

PURPOSE

We report four eyes of three glaucomatous patients who underwent trabeculectomy using topical mitomycin C. These eyes subsequently developed hypotony maculopathy. Snellen visual acuity decreased to 20/200 or worse in all cases. When the hypotony maculopathy persisted for 6-24 weeks and was unresponsive to nonsurgical therapies, we performed a second surgical procedure consisting of resuturing of the trabeculectomy scleral flap, closing the conjunctiva in its original position.

METHODS

The limbal-based conjunctival flap was reopened and the original scleral trabeculectomy flap was located. This flap was resutured to surrounding sclera, presumably limiting filtration.

RESULTS

This surgical revision increased the intraocular pressure, reversing the hypotony, and resulted in improved visual acuity to 20/25 or better in all cases with intraocular pressures between 6 and 17 mm Hg without intraocular pressure-lowering medications. The minimum follow-up after revision is 18 months.

CONCLUSION

There seems to be a definite relationship between the elevation of intraocular pressure and reversal of the macular damage associated with hypotony maculopathy. The visual outcome we experienced following resuturing of the scleral flap after persistent hypotony appears excellent in the treatment of a complication that is difficult to reverse. This technique has potential and should be strongly considered as a possible therapy in the management of hypotony maculopathy.

摘要

目的

我们报告了3例青光眼患者的4只眼,这些眼接受了局部应用丝裂霉素C的小梁切除术。这些眼随后发生了低眼压性黄斑病变。所有病例的Snellen视力均下降至20/200或更差。当低眼压性黄斑病变持续6 - 24周且对非手术治疗无反应时,我们进行了第二次手术,包括重新缝合小梁切除的巩膜瓣,将结膜原位关闭。

方法

重新打开以角膜缘为基底的结膜瓣,找到原来的巩膜小梁切除瓣。将此瓣重新缝合至周围巩膜,推测可限制滤过。

结果

此次手术修复使眼压升高,低眼压得到逆转,并且在未使用降眼压药物的情况下,所有眼压在6至17 mmHg之间的病例视力均提高至20/25或更好。修复后的最短随访时间为18个月。

结论

眼压升高与低眼压性黄斑病变相关的黄斑损伤逆转之间似乎存在明确的关系。在治疗这种难以逆转的并发症时,我们在持续性低眼压后重新缝合巩膜瓣所获得的视力结果似乎很好。这项技术具有潜力,应被强烈视为治疗低眼压性黄斑病变的一种可能疗法。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验