Tucker S, Jones B, Collin R
Department of Oculoplastic & Reconstructive Surgery, Moorfields Eye Hospital, London, UK.
Eye (Lond). 1996;10 ( Pt 3):310-4. doi: 10.1038/eye.1996.65.
Congenital anophthalmos and microphthalmos are rare conditions which can have associated pathology in the second eye and/or systemic anomalies. A retrospective review of 77 patients with congenital anophthalmos or microphthalmos seen at Moorfields Eye Hospital over a 13 year period was performed. A detailed description of the ocular and systemic anomalies present in our series of patients is given, and the current understanding of the pathogenesis of congenital anophthalmos and microphthalmos is reviewed.
先天性无眼球和小眼球是罕见病症，可能伴有对侧眼的相关病变和/或全身异常。我们对 Moorfields 眼科医院在 13 年期间诊治的 77 例先天性无眼球或小眼球患者进行了回顾性研究。本文详细描述了我们系列患者中存在的眼部和全身异常情况，并对先天性无眼球和小眼球发病机制的当前认识进行了综述。
