Soni B P, Sherertz E F
Department of Dermatology, Bowman, Gray School of Medicine of Wake Forest University, Winston-Salem, NC, USA.
Am J Contact Dermat. 1996 Jun;7(2):116-7.
A 51-year-old production mechanic for a pharmaceutical company complained of a dermatitis involving his hands. The onset of the eruption coincided with when he was placed on the production packing line for azathioprine tablets. Patch testing showed a positive allergic reaction only to azathioprine diluted in petrolatum. A pharmaceutical product such as azathioprine may need to be considered as a cause for allergic contact dermatitis in patients with a history of exposure during the manufacturing process.
一名51岁的制药公司生产机械师抱怨双手出现皮炎。皮疹的发作与他被安排到硫唑嘌呤片生产包装线上的时间一致。斑贴试验显示仅对凡士林稀释的硫唑嘌呤有阳性过敏反应。对于有在制造过程中接触史的患者，像硫唑嘌呤这样的药品可能需要被视为过敏性接触性皮炎的一个病因。
