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术中使用酮咯酸与扁桃体切除术后出血

Intraoperative ketorolac and posttonsillectomy bleeding.

作者信息

Judkins J H, Dray T G, Hubbell R N

机构信息

Department of Surgery, University of Vermont, Burlington, USA.

出版信息

Arch Otolaryngol Head Neck Surg. 1996 Sep;122(9):937-40. doi: 10.1001/archotol.1996.01890210017004.

Abstract

OBJECTIVE

To determine the occurrence of posttonsillectomy bleeding in patients who received intraoperative ketorolac tromethamine.

DESIGN

Retrospective analysis.

SETTING

Academic tertiary care center.

PATIENTS

Three hundred eleven patients who underwent tonsillectomy in an 18-month period.

MAIN OUTCOME MEASURE

Occurrence of bleeding complications in patients who received ketorolac during tonsillectomy.

RESULTS

Fifty-eight of 311 patients who underwent tonsillectomy received intraoperative ketorolac with an overall postoperative bleeding rate of 17%. This high rate of bleeding complications compares with 4.4% in the remaining 253 patients who received traditional opioid analgesics.

CONCLUSIONS

Until further controlled studies have been conducted, the use of ketorolac in patients undergoing tonsillectomy should be avoided because of the increased incidence of postoperative bleeding complications.

摘要

目的

确定术中接受酮咯酸氨丁三醇的患者扁桃体切除术后出血的发生率。

设计

回顾性分析。

地点

学术性三级医疗中心。

患者

在18个月期间接受扁桃体切除术的311例患者。

主要观察指标

扁桃体切除术中接受酮咯酸的患者出血并发症的发生率。

结果

311例接受扁桃体切除术的患者中有58例术中接受了酮咯酸,术后总体出血率为17%。与其余253例接受传统阿片类镇痛药的患者4.4%的出血率相比,该出血并发症发生率较高。

结论

在进一步的对照研究开展之前,由于术后出血并发症发生率增加,应避免在接受扁桃体切除术的患者中使用酮咯酸。

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