宫颈癌：快速自旋回波序列和脂肪抑制技术能否改善0.5T磁共振成像的肿瘤分期？
Cervical carcinoma: do fast SE and fat suppression techniques improve MR tumor staging at 0.5 T?
作者信息
Postema S, Peters L A, Hermans J, Trimbos J B, Pattynama P M
机构信息
Department of Radiology, Leiden University Hospital, The Netherlands.
出版信息
J Comput Assist Tomogr. 1996 Sep-Oct;20(5):807-11. doi: 10.1097/00004728-199609000-00024.
PURPOSE
Our goal was to compare fast SE (FSE) with T2-weighted conventional SE (CSE) MRI of cervical carcinoma and to evaluate the potential advantage of fat suppression technique.
METHODS
We compared the tissue contrasts between cervical carcinoma and the surrounding tissues in 24 patients. The following MR sequences were obtained at 0.5 T: T1-weighted CSE (450/20 ms), T2-weighted CSE (2,500/45, 90), and T2-weighted FSE (4,800/120), the latter with and without fat suppression using fat-selective prepulses.
RESULTS
T2-weighted FSE MRI provided significantly better contrasts between tumor and normal cervical stroma (p < 0.001) and between tumor and rectum wall (p < 0.05) than T2-weighted CSE MRI. T1-weighted SE MRI gave the highest tissue contrast between tumor and parametrial tissue (p < 0.001). Fat suppression did not further improve tissue contrasts.
CONCLUSION
MR staging of cervical carcinoma is best done with the combination of T1-weighted SE and T2-weighted FSE images, without additional fat suppression.
目的
我们的目标是比较快速自旋回波（FSE）与常规自旋回波（CSE）T2加权磁共振成像（MRI）在宫颈癌中的应用，并评估脂肪抑制技术的潜在优势。
方法
我们比较了24例患者宫颈癌组织与周围组织之间的组织对比度。在0.5T磁场下获得以下MR序列：T1加权CSE（450/20ms）、T2加权CSE（2500/45,90）和T2加权FSE（4800/120），后者使用脂肪选择性预脉冲进行脂肪抑制和不进行脂肪抑制。
结果
与T2加权CSE MRI相比，T2加权FSE MRI在肿瘤与正常宫颈基质之间（p<0.001）以及肿瘤与直肠壁之间（p<0.05）提供了明显更好的对比度。T1加权SE MRI在肿瘤与宫旁组织之间提供了最高的组织对比度（p<0.001）。脂肪抑制并未进一步改善组织对比度。
结论
宫颈癌的MR分期最好结合T1加权SE和T2加权FSE图像进行，无需额外的脂肪抑制。
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