Van Splunder P, Huisman T W, DeRidder M A, Wladimiroff J W
Department of Obstetrics and Gynecology, University Hospital Rotterdam-Dijkzigt, The Netherlands.
Pediatr Res. 1996 Jul;40(1):158-62. doi: 10.1203/00006450-199607000-00027.
Our purpose was to study the nature and gestational age dependency of fetal venous Doppler flow velocity wave forms and their relationship with fetal arterial wave forms in early pregnancy. Venous and arterial Doppler recordings were performed in 262 normal singleton pregnancies according to a cross-sectional study design at 8-20 wk of gestation. A statistically significant age-dependent increase is established for the umbilical vein, ductus venosus, and inferior vena cava time-averaged velocity. Umbilical venous pulsatile flow patterns are observed up to 15 wk of gestation. The pulsatility index for veins in all three venous vessels displays a gestational age-dependent reduction. No relation can be established between the pulsatility index for veins and the pulsatility index in the descending aorta and umbilical artery. This may be explained by the fact that the pulsatility index for veins reflects cardiac ventricular preload, whereas the pulsatility index in the arterial vessels reflects downstream impedance at fetal placental level.
我们的目的是研究妊娠早期胎儿静脉多普勒血流速度波形的性质、孕周依赖性及其与胎儿动脉波形的关系。根据横断面研究设计，在262例正常单胎妊娠的孕8至20周进行静脉和动脉多普勒记录。脐静脉、静脉导管和下腔静脉的时间平均速度呈现出具有统计学意义的随年龄增长而增加的趋势。在妊娠15周前可观察到脐静脉搏动性血流模式。所有三根静脉血管中静脉的搏动指数均呈现出孕周依赖性降低。静脉搏动指数与降主动脉和脐动脉搏动指数之间无相关性。这可能是因为静脉搏动指数反映心室前负荷，而动脉血管搏动指数反映胎儿胎盘水平的下游阻抗。
