Uğur M, Turan C, Vicdan K, Ekici E, Oğuz O, Gökmen O
Dr. Zekai Tahir Burak Women's Hospital, Ankara, Turkey.
Aust N Z J Obstet Gynaecol. 1996 May;36(2):186-9. doi: 10.1111/j.1479-828x.1996.tb03283.x.
Chronic ectopic pregnancy is a form of tubal pregnancy in which salient minor ruptures or abortions of an ectopic pregnancy instead of a single episode of bleeding, incites an inflammatory response often leading to the formation of a pelvic mass. Its clinical features are often confusing, and laboratory evaluations are often misleading. Surgery for chronic ectopic pregnancy is frequently difficult since chronic inflammatory changes and adhesions distort the normal anatomy. In the present retrospective study, its incidence was found to be 20.3% (n = 62) in a series of 305 ectopic pregnancies. A pelvic mass of varying sonographic appearance, mostly with a nonhomogenous echo pattern, was demonstrated in all 55 patients in whom transvaginal sonographic evaluation was performed preoperatively. Although most of the patients [91.9% (n = 57)] had a positive serum beta HCG value, 5 patients had a negative test value. Laparotomy resulted in 40 salpingectomies, 19 salpingo-oophorectomies, and 3 total abdominal hysterectomies with salpingo-oophorectomies. One patient had a incidental cystotomy and 2 an incidental colotomy. We conclude that chronic ectopic pregnancy is not rare although little is mentioned about it as a clinical entity in the gynaecological literature. With increased awareness of its mildly symptomatic and protracted clinical course, and with proper interpretation of laboratory evaluations, a preoperative diagnosis can be made in the majority of the cases.
慢性异位妊娠是输卵管妊娠的一种形式,其中异位妊娠出现明显的微小破裂或流产,而非单次出血,会引发炎症反应,常导致盆腔肿块形成。其临床特征往往令人困惑,实验室检查结果也常常具有误导性。由于慢性炎症变化和粘连会使正常解剖结构变形,慢性异位妊娠的手术通常很困难。在本回顾性研究中,在305例异位妊娠病例系列中,其发生率为20.3%(n = 62)。术前进行经阴道超声评估的所有55例患者均显示出超声表现各异的盆腔肿块,大多具有不均匀回声模式。尽管大多数患者[91.9%(n = 57)]血清β-HCG值呈阳性,但有5例患者检测值为阴性。剖腹手术导致40例行输卵管切除术、19例行输卵管卵巢切除术以及3例行全腹子宫切除术加输卵管卵巢切除术。1例患者意外发生膀胱切开术,2例意外发生结肠切开术。我们得出结论,慢性异位妊娠并不罕见,尽管在妇科文献中很少将其作为一种临床实体提及。随着对其症状轻微且病程迁延的认识增加,以及对实验室检查结果的正确解读,大多数病例能够在术前做出诊断。