Brenner W I, Lieberman A N
Ann Thorac Surg. 1977 Jul;24(1):80-2. doi: 10.1016/s0003-4975(10)64577-8.
A patient who underwent cardiopulmonary bypass developed a syndrome of malignant hypertension with agitated delirium, unresponsive to antihypertensive agents, following abrupt withdrawal of clonidine. The literature on this syndrome is reviewed with emphasis placed on prompt recognition. The syndrome can be reversed by resumption of clonidine administration and can be prevented by maintenance of clonidine levels through the perioperative period.
一名接受体外循环的患者在突然停用可乐定后出现恶性高血压综合征，并伴有激越性谵妄，对抗高血压药物无反应。本文回顾了关于该综合征的文献，重点强调了及时识别。通过恢复使用可乐定可逆转该综合征，并且在围手术期维持可乐定水平可预防该综合征。
