Hughes P L, Morse R M
Mayo Clin Proc. 1985 Jan;60(1):47-9. doi: 10.1016/s0025-6196(12)65281-1.
Clonidine hydrochloride masked the signs of sedative withdrawal when it was used in detoxification of a patient with sedative-opiate-amphetamine dependence. Therefore, we urge caution in the use of clonidine in mixed-drug detoxification regimens.