Pearson E G, Andreasen C B, Blythe L L, Craig A M
College of Veterinary Medicine, Oregon State University, Corvallis 97331, USA.
J Am Vet Med Assoc. 1996 Sep 15;209(6):1137-42.
A group of 6- to 8-month-old calves developed head tremors, stiff gait, and staggering after consuming ryegrass straw that contained 3,711 micrograms of lolitrem-B/ kg. Signs were consistent with ryegrass staggers syndrome. At necropsy, all calves examined had atypical interstitial pneumonia, with marked emphysema and bullae. Infectious organisms and pneumotoxins were not identified. Experimentally, feeding the same ryegrass straw to age-matched calves induced similar neurologic signs, but did not result in pneumonic lesions. The high concentration of lolitrem-B in the straw or other, undefined factors, such as feed changes, may have contributed to the atypical interstitial pneumonia in the naturally exposed calves.
一群6至8个月大的小牛在食用了每千克含有3711微克洛替米B的黑麦草秸秆后，出现头部震颤、步态僵硬和蹒跚不稳的症状。这些症状与黑麦草蹒跚综合征相符。尸检时，所有接受检查的小牛均患有非典型间质性肺炎，并伴有明显的肺气肿和肺大疱。未发现感染性生物体和肺毒素。通过实验，给年龄匹配的小牛喂食相同的黑麦草秸秆会引发类似的神经症状，但未导致肺部病变。秸秆中高浓度的洛替米B或其他不明因素，如饲料变化，可能是导致自然接触秸秆的小牛患非典型间质性肺炎的原因。
