Savino P J, Glaser J S, Cassady J
Arch Ophthalmol. 1977 Jul;95(7):1185-9. doi: 10.1001/archopht.1977.04450070083005.
A follow-up study was performed to determine the general prognosis for health and life in 86 patients with retinal artery occlusion or ophthalmoscopically observed retinal cholesterol emboli, not subjected to surgery. Survivorship rates and incidence of subsequent cerebrovascular disease were calculated and compared to expected survivorship rate of an age-and sex-matched population. Results were as follows: the patient group with retinal stroke as a whole showed a statistically significant diminished survivorship rate from the third year onward; patients with retinal occlusions without visible emboli had a survivorship rate comparable to the matched control; but patients with visible emboli demonstrated a strikingly diminished survivorship rate. In the study group, the combined time corrected annual stroke mortality was 1,695 per 100,000 (four to five times greater than expected), but the largest single cause of death was cardiovascular disease.
进行了一项随访研究,以确定86例未接受手术治疗的视网膜动脉阻塞或经检眼镜观察到视网膜胆固醇栓子患者的总体健康和生命预后。计算了生存率和随后脑血管疾病的发病率,并与年龄和性别匹配人群的预期生存率进行比较。结果如下:整个视网膜卒中患者组从第三年起生存率在统计学上显著降低;无可见栓子的视网膜阻塞患者的生存率与匹配对照组相当;但有可见栓子的患者生存率显著降低。在研究组中,经时间校正的年卒中合并死亡率为每10万人1695例(比预期高4至5倍),但最大的单一死因是心血管疾病。