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RTX毒素的生物学效应:脂多糖的潜在作用

Biological effects of RTX toxins: the possible role of lipopolysaccharide.

作者信息

Czuprynski C J, Welch R A

机构信息

Department of Pathobiological Sciences, School of Veterinary Medicine, Madison, Wisconsin, USA.

出版信息

Trends Microbiol. 1995 Dec;3(12):480-3. doi: 10.1016/s0966-842x(00)89016-2.

DOI:10.1016/s0966-842x(00)89016-2
PMID:8800842
Abstract

RTX toxins are a family of related exotoxins with hemolytic, leukotoxi c and leukocyte-stimulating activities that are produced by a diverse array of Gram-negative bacteria. Lipopolysaccharide might be required for the maximal production of some RTX toxins and might be a cofactor in some of the biological effects of RTX toxins.

摘要

RTX毒素是一类相关的外毒素家族,具有溶血、白细胞毒性和刺激白细胞活性,由多种革兰氏阴性细菌产生。脂多糖可能是某些RTX毒素最大产量所必需的,并且可能是RTX毒素某些生物学效应的辅助因子。

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