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肾上腺微波消融:实验研究与临床应用

Microwave ablation of the adrenal gland: experimental study and clinical application.

作者信息

Kigure T, Harada T, Satoh Y, Fujieda N, Wakayama Y

机构信息

Department of Urology, Akita University School of Medicine, Japan.

出版信息

Br J Urol. 1996 Feb;77(2):215-20. doi: 10.1046/j.1464-410x.1996.86210.x.

Abstract

OBJECTIVE

To evaluate the heating effect of microwave irradiation on the dog adrenal gland and to assess the clinical feasibility of microwave ablation of adrenal tumours.

MATERIALS AND METHODS

The thermal distribution and histology were evaluated after dog adrenal glands were irradiated at different intensities with microwaves. Irradiation at 70 W for 30 s was also performed after laparotomy, on the adrenal tumour of a patient with primary aldosteronism.

RESULTS

Microwave irradiation at 70 W for 30 s provided a sufficiently high temperature to produce coagulation within a 5 mm radius of the microwave electrode. The adrenal tumor in the patient with primary aldosteronism was coagulated successfully by this dose of microwave irradiation.

CONCLUSION

Microwave ablation of the adrenal gland may be clinically applicable in the treatment of adrenal tumours.

摘要

目的

评估微波辐射对犬肾上腺的加热效果,并评估微波消融肾上腺肿瘤的临床可行性。

材料与方法

用不同强度的微波照射犬肾上腺后,评估其热分布和组织学情况。剖腹手术后,还对一名原发性醛固酮增多症患者的肾上腺肿瘤进行了70W照射30s的操作。

结果

70W照射30s能使微波电极周围5mm半径范围内产生足够高的温度以形成凝固。该剂量的微波照射成功使原发性醛固酮增多症患者的肾上腺肿瘤发生凝固。

结论

肾上腺微波消融在肾上腺肿瘤治疗中可能具有临床应用价值。

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