Kayigil O, Atahan O, Metin A
Urology Clinics of TCDD, Ankara Hospital, Turkey.
Br J Urol. 1996 Feb;77(2):261-5. doi: 10.1046/j.1464-410x.1996.86017.x.
To determine whether the pattern of discoordination (an increase in electrical activity of the corpus cavernosum after an intracavernous injection with papaverine and which results in the contraction of the cavernous smooth muscles instead of relaxation) is an aetiological factor in veno-occlusive dysfunction (VOD).
Electromyography of the corpus cavernosum was performed before and after an intracavernous injection with 60 mg papaverine in 45 patients diagnosed as having venogenic erectile dysfunction by colour Doppler ultrasonic flowmetry and dynamic infusion cavernosometry and cavernosography. Cavernosometric values were compared in patients with and with no pattern of discoordination.
A pattern of discoordination occurred in 14 patients (31%). There were significant differences in the cavernosometric values of patients with and with no discoordination. A poor response to papaverine and greater venous leakage were observed in the patients showing discoordination.
The pattern of discoordination diagnosed by electromyography after injection with papaverine may explain some aspects of VOD and highlights the importance of performing electromyography of the corpus cavernosum in the diagnostic evaluation of VOD.
确定不协调模式（海绵体内注射罂粟碱后海绵体电活动增加，导致海绵体平滑肌收缩而非松弛）是否为静脉闭塞功能障碍（VOD）的病因。
对45例经彩色多普勒超声血流测定、动态灌注海绵体测压和海绵体造影诊断为静脉性勃起功能障碍的患者，在海绵体内注射60mg罂粟碱前后进行海绵体肌电图检查。比较有无不协调模式患者的海绵体测压值。
14例患者（31%）出现不协调模式。有无不协调模式患者的海绵体测压值存在显著差异。在出现不协调的患者中观察到对罂粟碱反应不佳和静脉漏增加。
注射罂粟碱后通过肌电图诊断的不协调模式可能解释VOD的某些方面，并突出了在VOD诊断评估中进行海绵体肌电图检查的重要性。
