Van den Bosch T, Vandendael A, Wranz P A, Lombard C J
Department of Obstetrics and Gynecology, University of Stellenbosch, Tygerberg Hospital, South Africa.
Eur J Obstet Gynecol Reprod Biol. 1996 Jan;64(1):91-4. doi: 10.1016/0301-2115(95)02274-0.
To evaluate the accuracy of Endopap- and Pipelle-sampling in the diagnosis of postmenopausal disease.
Observational study in the setting of a University Hospital. One hundred and six consecutive postmenopausal women presenting with uterine bleeding or endometrial cells on cervical cytology underwent an Endopap sampling as well as a Pipelle biopsy. Thereafter, 89 of those women underwent a hysteroscopy and curettage (n = 71) or a hysterectomy (n = 18). The diagnostic accuracy of Pipelle and Endopap was assessed against the final diagnosis.
Endometrial carcinoma was found in five cases (6%), benign disease in 34 (38%). The sensitivity of Endopap and Pipelle for the detection of endometrial disease was 56 and 51%, respectively, with a specificity of 94 and 100%, respectively. The sensitivity for endometrial carcinoma was 80% for Endopap and 100% for Pipelle.
Our data tend to favor Pipelle against Endopap as diagnostic tool in endometrial disease in symptomatic postmenopausal women.
评估内膜取样器（Endopap）和 Pipelle 取样在绝经后疾病诊断中的准确性。
在一所大学医院进行的观察性研究。106 名连续出现子宫出血或宫颈细胞学检查发现子宫内膜细胞的绝经后女性接受了内膜取样器取样以及 Pipelle 活检。此后，其中 89 名女性接受了宫腔镜检查及刮宫术（n = 71）或子宫切除术（n = 18）。根据最终诊断评估 Pipelle 和内膜取样器的诊断准确性。
发现 5 例（6%）子宫内膜癌，34 例（38%）为良性疾病。内膜取样器和 Pipelle 检测子宫内膜疾病的敏感性分别为 56%和 51%，特异性分别为 94%和 100%。内膜取样器检测子宫内膜癌的敏感性为 80%，Pipelle 为 100%。
我们的数据倾向于支持在有症状的绝经后女性子宫内膜疾病诊断中，Pipelle 比内膜取样器更具优势。
