伴有8；21染色体易位的急性髓性白血病患者胸椎硬脊膜外粒细胞肉瘤
Extradural granulocytic sarcoma of the thoracic spine in acute myelogenous leukemia with 8; 21 chromosome translocation.
作者信息
Aizawa T, Kokubun S, Hatori M, Kashimoto O, Ichinohasama R
机构信息
Department of Orthopaedic Surgery, Tohoku Unversity School of Medicine, Sendai, Japan.
出版信息
Tohoku J Exp Med. 1996 Apr;178(4):431-6. doi: 10.1620/tjem.178.431.
We report a case of a 19-year-old male with an extradural granulocytic sarcoma at T5/6 to T7 demonstrated by MRI. He recovered from paraplegia that had progressed rapidly after excision of the tumor as an emergency operation. Histopathological studies disclosed granulocytic sarcoma. Both peripheral blood and bone marrow examinations revealed acute myelogenous leukemia. The karyotype of the bone marrow showed 45, X, -Y, t (8; 21) (q22; q22).
我们报告一例19岁男性，MRI显示T5/6至T7水平存在硬膜外粒细胞肉瘤。作为急诊手术切除肿瘤后，他从迅速进展的截瘫中康复。组织病理学研究显示为粒细胞肉瘤。外周血和骨髓检查均显示急性髓系白血病。骨髓核型显示为45,X,-Y,t(8;21)(q22;q22)。
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