Nomoto Y, Kawaguchi Y, Kubo H, Hirano H, Sakai S, Kurokawa K
Department of Internal Medicine School of Medicine, Tokai University, Isehara City, Japan.
Am J Kidney Dis. 1996 Sep;28(3):420-7. doi: 10.1016/s0272-6386(96)90501-6.
Patients undergoing continuous ambulatory peritoneal dialysis (CAPD) who developed sclerosing encapsulating peritonitis (SEP) were retrospectively studied in 130 centers in Japan. Among 6,923 patients undergoing CAPD between 1980 and 1994 only 62 (0.9%) given CAPD developed SEP. There were 38 men and 24 women, ranging in age from 20 to 87 years (average age, 48.3 years). These 62 patients developed SEP 10 to 138 months (average, 65.4 months) after starting CAPD. The average frequency of peritonitis before developing SEP was 3.3 times. Five of the 62 patients with SEP had no history of peritonitis, and 27 (43.5%) of them died of various causes in the study period. The major causes of death were almost invariably related to problems concerning bowel obstruction or complications of surgery, such as malnutrition or septicemia. It was concluded that SEP is one of the most serious complications of CAPD, and constant surveillance is necessary to detect SEP in patients during CAPD.
日本130个中心对接受持续性非卧床腹膜透析（CAPD）并发硬化性包裹性腹膜炎（SEP）的患者进行了回顾性研究。在1980年至1994年间接受CAPD治疗的6923例患者中，仅有62例（0.9%）发生了SEP。其中男性38例，女性24例，年龄在20岁至87岁之间（平均年龄48.3岁）。这62例患者在开始CAPD治疗10至138个月（平均65.4个月）后发生了SEP。发生SEP前腹膜炎的平均发作频率为3.3次。62例SEP患者中有5例无腹膜炎病史，其中27例（43.5%）在研究期间死于各种原因。主要死亡原因几乎都与肠梗阻问题或手术并发症有关，如营养不良或败血症。得出的结论是，SEP是CAPD最严重的并发症之一，在CAPD患者中持续监测以发现SEP是必要的。
