Gibertson E O, Hunt S J, Spellman M C
University of California, San Diego, School of Medicine, Division of Dermatology 92103, USA.
Cutis. 1996 Jun;57(6):437-40.
Cutaneous T-cell lymphoma (CTCL) is significantly less common than B-cell lymphoma in patients with acquired immunodeficiency syndrome (AIDS). Periocular involvement by CTCL usually occurs in the setting of more widespread plaque or tumor-stage disease; therefore, CTCL localized solely to the periocular region is rare. We report the case of a 38-year-old Hispanic woman with AIDS and an enlarging tumor of the left upper eyelid. The clinical differential diagnosis included various infections and neoplasms. Examination of an incisional biopsy specimen revealed a dense infiltrate of atypical lymphocytes that labeled as T cells with use of the immunoperoxidase technique. The tumor subsequently regressed with local radiotherapy. Eyelid CTCL is reviewed and the differential diagnosis of eyelid lesions is reviewed.
皮肤T细胞淋巴瘤(CTCL)在获得性免疫缺陷综合征(AIDS)患者中比B细胞淋巴瘤明显少见。CTCL累及眼周通常发生在更广泛的斑块或肿瘤期疾病背景下;因此,仅局限于眼周区域的CTCL很罕见。我们报告一例38岁患有AIDS的西班牙裔女性,其左上眼睑有一不断增大的肿瘤。临床鉴别诊断包括各种感染和肿瘤。对手术活检标本的检查显示有密集的非典型淋巴细胞浸润,使用免疫过氧化物酶技术标记为T细胞。该肿瘤随后通过局部放疗消退。本文对眼睑CTCL进行了综述,并对眼睑病变的鉴别诊断进行了综述。