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与人类免疫缺陷病毒感染相关的皮肤非亲表皮性淋巴瘤

Cutaneous non-epidermotropic lymphoma associated with human immunodeficiency virus infection.

作者信息

Viraben R, Brousset P, Aquilina C, Lamant L

机构信息

Department of Dermatology, Purpan and La Grave Hospital, Toulouse, France.

出版信息

Clin Exp Dermatol. 1997 Nov;22(6):262-4.

PMID:9604450
Abstract

A case of pure non-epidermotropic cutaneous lymphoma in a human immunodeficiency virus-infected patient is reported following a viral opportunistic infection [cytomegalovirus (CMV) hepatitis]. The lymphoid infiltrate was Epstein-Barr virus and CMV negative with a CD30-positive T-cell phenotype. Molecular analysis demonstrated T cell receptor gene rearrangement, but a non-aggressive disease course was noted supporting a cautious therapeutic approach in this case.

摘要

报告了1例人类免疫缺陷病毒感染患者在发生病毒机会性感染(巨细胞病毒(CMV)肝炎)后出现的纯非亲表皮性皮肤淋巴瘤。淋巴细胞浸润为EB病毒和CMV阴性,具有CD30阳性T细胞表型。分子分析显示T细胞受体基因重排,但注意到疾病进程不具侵袭性,支持对此病例采取谨慎的治疗方法。

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