Zamore P D, Lehmann R
Department of Chemistry, Massachusetts Institute of Technology, Cambridge 02139, USA.
Curr Biol. 1996 Jul 1;6(7):773-5. doi: 10.1016/s0960-9822(02)00591-2.
Translation of the transcription factor caudal is repressed at the anterior end of the Drosophila embryo. Surprisingly, the DNA-binding homeodomain of the transcription factor Bicoid mediates this repression by binding caudal mRNA.
转录因子尾型在果蝇胚胎前端受到抑制。令人惊讶的是,转录因子双胸的DNA结合同源结构域通过结合尾型mRNA介导了这种抑制作用。