缩小与DNA连接酶的差距。
Closing the gap on DNA ligase.
作者信息
Shuman S
机构信息
Molecular Biology Program, Sloan-Kettering Institute, New York, NY 10021, USA.
出版信息
Structure. 1996 Jun 15;4(6):653-6. doi: 10.1016/s0969-2126(96)00070-6.
PMID:8805556
Abstract
The crystal structure of T7 DNA ligase complexed with ATP illuminates the mechanism of covalent catalysis by a superfamily of nucleotidyl transferases that includes the ATP-dependent polynucleotide ligases and the GTP-dependent mRNA capping enzymes.
摘要
与ATP复合的T7 DNA连接酶的晶体结构揭示了一个核苷酸转移酶超家族的共价催化机制，该超家族包括ATP依赖的多核苷酸连接酶和GTP依赖的mRNA加帽酶。
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