Tabata N, Tanaka R, Suga S, Mitani Y, Nakano T, Ido M, Azuma E, Ito M, Hamazaki M, Shiraishi T, Sakurai M
Department of Pediatrics, Mie University School of Medicine, Japan.
Bone Marrow Transplant. 1996 Jun;17(6):1167-9.
Massive rhabdomyolysis followed by myocardial necrosis was observed in a 14-year-old patient undergoing allogeneic bone marrow transplantation for severe aplastic anemia. Rhabdomyolysis was preceded by the administration of cyclophosphamide as part of a preparative regimen for transplantation Although the specific etiology of this rhabdomyolysis is still unknown, an association with high-dose cyclophosphamide should be noted.
在一名因严重再生障碍性贫血接受异基因骨髓移植的14岁患者中，观察到了大面积横纹肌溶解随后出现心肌坏死的情况。横纹肌溶解发生在作为移植预处理方案一部分给予环磷酰胺之后。虽然这种横纹肌溶解的具体病因仍不清楚，但应注意到它与高剂量环磷酰胺有关。
