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对尼加拉瓜东部加里富纳人使用的药用植物进行生物活性化合物筛选。

Screening of medicinal plants used by the Garífuna of eastern Nicaragua for bioactive compounds.

作者信息

Coe F G, Anderson G J

机构信息

Department of Ecology and Evolutionary Biology, University of Connecticut, Storrs 06269-3043, USA.

出版信息

J Ethnopharmacol. 1996 Jul 26;53(1):29-50. doi: 10.1016/0378-8741(96)01424-9.

DOI:10.1016/0378-8741(96)01424-9
PMID:8807474
Abstract

As part of a larger study of the plants used by the Garífuna of eastern Nicaragua, the 229 species representing 177 genera and 72 families used for medicinal purposes were assayed for the presence of bioactive compounds. A review of the literature for alkaloids and glycosides showed that 113 species contained at least one of these bioactive compounds. The remaining 116 species not previously cited were tested for alkaloids with Dragendorff's reagent; 51 contained alkaloids. The combined results show that 72% of the species the Garífuna use medicinally have at least one alkaloid or glycoside. Tests to explore pharmacological activity of compounds from selected species represent the next step to determining efficacy and application of these medicinals.

摘要

作为对尼加拉瓜东部加里富纳人使用的植物进行的一项更大规模研究的一部分,对用于药用的代表177个属和72个科的229种植物进行了生物活性化合物检测。对生物碱和糖苷的文献综述表明,113种植物至少含有其中一种生物活性化合物。对之前未提及的其余116种植物用碘化铋钾试剂进行生物碱检测;其中51种含有生物碱。综合结果表明,加里富纳人药用的植物中有72%至少含有一种生物碱或糖苷。探索选定植物化合物药理活性的测试是确定这些药物疗效和应用的下一步。

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