Brown R L, Henke A, Greenhalgh D G, Warden G D
Shriners Burns Institute, Cincinnati, OH 45229, USA.
J Burn Care Rehabil. 1996 Jan-Feb;17(1):34-8. doi: 10.1097/00004630-199601000-00009.
Haloperidol has become the drug of choice for sedation of the acutely agitated, delirious adult patient in the critical care setting because of its well-documented efficacy and lack of major side effects. Its use in the critically ill pediatric patient with burns has not been described. To determine the safety and efficacy of haloperidol in this population, the medical records of 30 critically ill pediatric patients with burns treated with haloperidol during the period 1986 to 1992 were reviewed. Our findings support the safe and effective use of haloperidol to treat severe agitation and delirium in the critically ill pediatric patient. The intravenous route appears to be more effective than the enteral route and should be considered when rapid, acute control of agitation is required.
由于有充分的文献证明其疗效且无重大副作用，氟哌啶醇已成为重症监护环境中急性躁动、谵妄成年患者镇静的首选药物。其在重症烧伤儿科患者中的应用尚未见报道。为确定氟哌啶醇在该人群中的安全性和有效性，我们回顾了1986年至1992年期间30例接受氟哌啶醇治疗的重症烧伤儿科患者的病历。我们的研究结果支持氟哌啶醇用于治疗重症儿科患者的严重躁动和谵妄的安全性和有效性。静脉途径似乎比肠内途径更有效，在需要快速、急性控制躁动时应予以考虑。
