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医生指定的视觉模拟疼痛评分中最小临床重要差异。

The minimum clinically important difference in physician-assigned visual analog pain scores.

作者信息

Todd K H, Funk J P

机构信息

Department of Surgery, Emory University School of Medicine, Atlanta, GA, USA.

出版信息

Acad Emerg Med. 1996 Feb;3(2):142-6. doi: 10.1111/j.1553-2712.1996.tb03402.x.

DOI:10.1111/j.1553-2712.1996.tb03402.x
PMID:8808375
Abstract

OBJECTIVE

To determine the minimum clinically important difference in physician-assigned visual analog scale (VAS) pain scores.

METHODS

Physicians attending emergency medicine didactic conferences were enrolled in this descriptive study. The subjects sequentially reviewed 11 written scenarios describing patients in moderate to severe pain. The subjects rated their perceptions of each patient's pain on a 100-mm VAS, then contrasted this pain with that of the previous patient scenario. For these contrasts, the subjects chose one of five responses: "much less," "a little less," "about the same," "a little more," or "much more" pain. The minimum clinically important difference was defined as the difference between scores for scenario pairs in which one patient's pain was rated "a little less" or "a little more" severe.

RESULTS

There were 230 comparisons by 23 health professionals. Of these, 64 were judged "a little less," and 56 "a little more," painful. These 120 comparisons, with their pain score differences, were used to determine the minimum clinically important difference. Pain judged to be "a little less" or "a little more" severe was associated with a mean difference in VAS scores of 18 mm (95% CI 16-20 mm), corresponding to a decrement of 23% (95% CI 20-26%) from the more painful scenario.

CONCLUSIONS

Pain research outcomes involving a < 18-mm difference, or a 23% decrement in physician-assigned VAS pain scores, although statistically significant, may have little clinical importance.

摘要

目的

确定医生指定的视觉模拟量表(VAS)疼痛评分中最小的临床重要差异。

方法

参加急诊医学教学会议的医生参与了这项描述性研究。受试者依次回顾了11个描述中度至重度疼痛患者的书面病例。受试者在100毫米的VAS上对每个患者的疼痛感知进行评分,然后将该疼痛与前一个患者病例的疼痛进行对比。对于这些对比,受试者选择以下五种回答之一:“疼痛轻得多”、“疼痛稍轻”、“大致相同”、“疼痛稍重”或“疼痛重得多”。最小临床重要差异被定义为一个患者疼痛被评为“稍轻”或“稍重”的病例对评分之间的差异。

结果

23名卫生专业人员进行了230次比较。其中,64次被判断为“疼痛稍轻”,56次为“疼痛稍重”。这120次比较及其疼痛评分差异被用于确定最小临床重要差异。被判断为“稍轻”或“稍重”的疼痛与VAS评分的平均差异为18毫米(95%置信区间16 - 20毫米),相当于较疼痛病例减少了23%(95%置信区间20 - 26%)。

结论

疼痛研究结果中,若VAS疼痛评分差异<18毫米或降低23%,尽管在统计学上有显著意义,但可能临床重要性不大。

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