Okuno T, Tochigi H, Yanagawa M, Arima K, Kawamura J
Department of Urology, Mie University School of Medicine.
Hinyokika Kiyo. 1996 Jul;42(7):487-91.
Nineteen patients with renal cell carcinoma with tumor extension into the inferior vena cava (IVC) were investigated between January, 1973 and March, 1994. The patients were between 50 and 78 years old with a mean of 65.9 years. The male to female ratio was 1.7 to 1. Thirteen tumors were on the right side and 6 on the left side. In 12 patients, both nephrectomy and removal of the tumor thrombus were performed. The survival rate in the operated group was 60% at 5 years. Histologically, 7 cases were diagnosed as clear cell subtype and 5 cases as granular cell subtype. From this study, an extended operative intervention such as radical nephrectomy combined with tumor thrombectomy of the IVC with or without cavectomy was suggested in the case of renal cell carcinoma without any other metastatic lesions and histopathologically of the clear cell subtype.
1973年1月至1994年3月期间，对19例肿瘤已侵犯下腔静脉（IVC）的肾细胞癌患者进行了调查。患者年龄在50至78岁之间，平均年龄为65.9岁。男女比例为1.7比1。13个肿瘤位于右侧，6个位于左侧。12例患者同时进行了肾切除术和肿瘤血栓切除术。手术组5年生存率为60%。组织学上，7例被诊断为透明细胞亚型，5例为颗粒细胞亚型。根据这项研究，对于没有任何其他转移病变且组织病理学为透明细胞亚型的肾细胞癌患者，建议进行扩大手术干预，如根治性肾切除术联合IVC肿瘤血栓切除术，可选择或不进行腔静脉切除术。
