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出生季节与精神分裂症:南半球数据

Season of birth and schizophrenia: southern hemisphere data.

作者信息

Berk M, Terre-Blanche M J, Maude C, Lucas M D, Mendelsohn M, O'Neill-Kerr A J

机构信息

Department of Psychiatry, University of the Witwatersrand Medical School, Parktown, Johannesburg, South Africa.

出版信息

Aust N Z J Psychiatry. 1996 Apr;30(2):220-2. doi: 10.3109/00048679609076097.

Abstract

OBJECTIVE

The association between winter birth and increased incidence of schizophrenia is well documented in the northern hemisphere. The present study examined season of birth and schizophrenia in a southern hemisphere population from a mild temperate climate.

METHOD

The seasonal incidence of birth in schizophrenic patients was compared, using Chi-squared tests, to normative population birth rates.

RESULTS

A statistically significant seasonal pattern, with a peak in late spring and early summer, was obtained.

CONCLUSION

This supports northern hemisphere findings regarding calendar month, but not season, of excess schizophrenic births. This has implications for viral and other aetiological hypotheses dependent on meteorological factors.

摘要

目的

在北半球,冬季出生与精神分裂症发病率增加之间的关联已有充分记载。本研究调查了来自温和温带气候的南半球人群的出生季节与精神分裂症之间的关系。

方法

使用卡方检验将精神分裂症患者的季节性出生发病率与正常人群出生率进行比较。

结果

获得了具有统计学意义的季节性模式,在春末和初夏达到峰值。

结论

这支持了北半球关于精神分裂症出生过多的日历月份而非季节的研究结果。这对依赖气象因素的病毒及其他病因假说具有启示意义。

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