Miller A B, Gaudette L A
Department of Preventive Medicine and Biostatistics, Faculty of Medicine, University of Toronto, Ontario, Canada.
Acta Oncol. 1996;35(5):607-16. doi: 10.3109/02841869609096994.
Low rates of skin cancer, both melanoma and non-melanoma, were observed in Inuit after 20 years of observation. Tumours of the brain and central nervous system, of the thyroid, bone and connective tissues and other specified sites occurred with rates similar to those in comparison populations in Denmark, Connecticut and Canada. These findings support that neither UV and ionizing radiation from nuclear fall-out, nor pollution of herbicides and pesticides in the Arctic area have yet had any noticeable impact on cancer risk. However, unspecified and secondary neoplasms constitute 7-8% of the total Circumpolar cancer incidence and the pattern of rare cancers must be interpreted with caution. Increased diagnostic efforts with a higher precision in the future are warranted.
经过20年的观察，因纽特人的皮肤癌（包括黑色素瘤和非黑色素瘤）发病率较低。脑和中枢神经系统、甲状腺、骨骼和结缔组织以及其他特定部位的肿瘤发病率与丹麦、康涅狄格州和加拿大的对照人群相似。这些发现表明，北极地区来自核沉降物的紫外线和电离辐射，以及除草剂和杀虫剂污染，尚未对癌症风险产生任何明显影响。然而，未明确分类的肿瘤和继发性肿瘤占环北极地区癌症总发病率的7-8%，对罕见癌症的发病模式必须谨慎解读。未来有必要加大诊断力度并提高诊断精度。
