Hammond C J, Chan W Y, Liu C S
Department of Ophthalmology, Addenbrooke's Hospital, Cambridge.
Br J Ophthalmol. 1996 Feb;80(2):164-7. doi: 10.1136/bjo.80.2.164.
AIMS/BACKGROUND: Interrupted corneal sutures are used routinely by many cataract and corneal surgeons. A slim compact knot facilitates burial and allows atraumatic suture removal, with decreased risk of wound dehiscence. The size and morphology of knots tied in different configurations were investigated.
10-0 nylon suture material was used to tie knots on porcine corneal cataract sections using 2/1/1 (reef and granny), 3/1/1, and 1/1/1/1 (slip knot) configurations. 10-0 Mersilene was used to tie 2/1/1 reef knots. Scanning electron micrographs of the knots were digitised and their maximal lengths and widths estimated. In addition, the area of each knot was calculated and used as an index of its volume.
2/1/1 reef knots were significantly smaller in all dimensions compared with the other knots (all p < 0.03) except for the maximal width of 2/1/1 granny knots which were no wider than the 2/1/1 granny knots. The Mersilene knots were larger than the nylon ones.
The use of 2/1/1 reef knots is recommended for corneal suturing.
目的/背景：许多白内障和角膜外科医生常规使用间断角膜缝线。纤细紧密的结便于埋藏，可实现无创伤拆线，且伤口裂开风险降低。研究了以不同构型打结的尺寸和形态。
使用10-0尼龙缝线材料，采用2/1/1（方结和奶奶结）、3/1/1和1/1/1/1（滑结）构型在猪角膜白内障切片上打结。使用10-0聚酯缝线来打2/1/1方结。将结的扫描电子显微镜图像数字化，并估计其最大长度和宽度。此外，计算每个结的面积，并将其用作体积指标。
与其他结相比，2/1/1方结在所有维度上均显著更小（所有p<0.03），但2/1/1奶奶结的最大宽度不宽于2/1/1方结。聚酯缝线结比尼龙缝线结更大。
建议角膜缝合时使用2/1/1方结。
