Möller A, Wetzel H, Niemöller E, Hopf R
Innere Abteilung, Krankenhaus Sachsenhausen, Frankfurt.
Dtsch Med Wochenschr. 1996 Feb 23;121(8):237-40. doi: 10.1055/s-2008-1043000.
A 70-year-old man, admitted for a haemorrhoid operation, suddenly went into circulatory shock (heart rate 150/min, blood pressure 100/70 mm Hg), necessitating transfer to an intensive care unit. His neck veins were prominent and he had a paradoxical pulse. Heart sounds were distant and there was an arrhythmia (atrial fibrillation in the ECG). No murmurs were heard. Breath sounds were decreased, especially in the lung bases.
Differential blood count showed 30% stab cells with 12,200 white cells per microliter. Erythrocyte sedimentation rate was 118 mm in the first hour, C-reactive protein was raised to 11.8 mg/dl. There was a partially compensated respiratory acidosis (pH 7.12; pO 93.4 mm Hg; pCO 16.3 mm Hg; base deficit -22.6 mmol/l). In the chest radiogram the cardiac silhouette was greatly enlarged bilaterally. The echocardiogram demonstrated a large pericardial perfusion with a "swinging heart".
At pericardial needle puncture 700 ml of amber-coloured fluid, containing pneumococci, were aspirated with immediate circulatory improvement. Penicillin, 10 mill.U twice daily for 13 days, was administered intravenously, followed by amoxycillin, 1 g three times daily by mouth, for a further 15 days. In addition he was given anti-inflammatory treatment with diclofenac and methylprednisolone. Despite this pericardial effusion recurred after 14 days and 600 ml of sterile fluid were removed. Subsequently the inflammatory signs disappeared. Three months later no effusion was present and there were no signs of constrictive pericarditis.
一名70岁男性因痔疮手术入院,突然发生循环性休克(心率150次/分钟,血压100/70 mmHg),需要转入重症监护病房。他的颈静脉怒张,存在奇脉。心音遥远,伴有心律失常(心电图显示为心房颤动)。未闻及杂音。呼吸音减弱,尤其是肺底部。
血常规显示杆状核细胞占30%,白细胞计数为每微升12200个。红细胞沉降率在第1小时为118 mm,C反应蛋白升高至11.8 mg/dl。存在部分代偿性呼吸性酸中毒(pH 7.12;pO₂ 93.4 mmHg;pCO₂ 16.3 mmHg;碱缺失-22.6 mmol/l)。胸部X线片显示双侧心影明显增大。超声心动图显示大量心包积液,心脏呈“摇摆征”。
心包穿刺抽出700 ml琥珀色液体,其中含有肺炎球菌,循环立即得到改善。静脉注射青霉素,每日2次,每次1000万单位,共13天,随后口服阿莫西林,每日3次,每次1 g,持续15天。此外给予双氯芬酸和甲泼尼龙进行抗炎治疗。尽管如此,14天后心包积液复发,抽出600 ml无菌液体。随后炎症体征消失。3个月后无积液,也无缩窄性心包炎的迹象。