Shoemaker W C, Wo C C, Bishop M H, Thangathurai D, Patil R S
Department of Emergency Medicine, King-Drew Medical Center, Los Angeles, CA, USA.
Acad Emerg Med. 1996 Jul;3(7):675-81. doi: 10.1111/j.1553-2712.1996.tb03489.x.
To evaluate the feasibility of multicomponent noninvasive hemodynamic monitoring in critical emergency patients and to compare this technique with simultaneous invasive monitoring by the pulmonary artery thermodilution catheter.
A prospective observational study was done comparing invasive monitoring and noninvasive monitoring in 60 critically ill or injured patients who required hemodynamic monitoring shortly after entering the ED of a university-affiliated country hospital. Cardiac output (CO) values measured by the standard thermo-dilution pulmonary artery catheter technique were compared with simultaneously obtained measurements using a noninvasive bioimpedance method. Concurrent measurements were made of pulse oximetry to screen pulmonary function and transcutaneous oximetry to assess tissue perfusion.
The impedance CO values closely approximated those for the thermodilution method; r 0.81, p < 0.001. Significant circulatory abnormalities, including hypotension, reduced cardiac index, arterial hemoglobin desaturation, tissue hypoxia, reduced O2 delivery, and consumption, were found in 54 of the 60 (90%) patients. The cardiac index decreased in 44% of the patients, the transcutaneous O2 decreased in 39%, and the O2 saturation by pulse oximetry fell in 22% during the observation period in the ED (commonly lasting 2-8 hours).
Noninvasive monitoring can provide hemodynamic and perfusion information previously available only by invasive thermodilution catheters. Such noninvasive monitoring can display continuous on-line real-time data, allowing immediate recognition of circulatory abnormalities and providing a means to titrate therapy to appropriate therapeutic goals.
评估多组分无创血流动力学监测在急危重症患者中的可行性,并将该技术与通过肺动脉热稀释导管进行的同步有创监测进行比较。
进行了一项前瞻性观察性研究,比较了60例急危重症或受伤患者的有创监测和无创监测,这些患者在进入一所大学附属医院急诊科后不久就需要进行血流动力学监测。将标准热稀释肺动脉导管技术测量的心输出量(CO)值与使用无创生物阻抗方法同时获得的测量值进行比较。同时进行脉搏血氧饱和度测定以筛查肺功能,进行经皮血氧饱和度测定以评估组织灌注。
阻抗法测得的CO值与热稀释法测得的值非常接近;r = 0.81,p < 0.001。在60例患者中的54例(90%)中发现了明显的循环异常,包括低血压、心脏指数降低、动脉血红蛋白饱和度降低、组织缺氧、氧输送和消耗减少。在急诊科观察期间(通常持续2 - 8小时),44%的患者心脏指数下降,39%的患者经皮氧分压下降,22%的患者脉搏血氧饱和度下降。
无创监测可以提供以前只有通过有创热稀释导管才能获得的血流动力学和灌注信息。这种无创监测可以显示连续的在线实时数据,使循环异常能够立即被识别,并提供一种手段来将治疗调整到适当的治疗目标。