Farrior J B, Nichols S W
University of South Florida, Tampa, USA.
Am J Otol. 1996 May;17(3):386-92.
Sculpted autologous ossicle and cortical bone grafts were the first materials successfully used to reconstruct the ossicular chain in chronic ear surgery. Over the last 20 years, the use of biocompatible implants has been popularized; as a result, bone grafts have fallen into disfavor with most otologists. To determine if autologous bone grafts remain stable with time, 115 cases in which autologous bone grafts were used between 1971 and 1984 were reviewed. Eighty patients underwent Type III tympanoplasty, stapes arch present. Thirty-five underwent Type IV tympanoplasty, stapes arch absent. Minimum follow-up was 2 years; 30 patients were followed for > or = 10 years. In Type III tympanoplasty, overall the initial air/bone gap was 19.7 dB at 6 months, with 59% of those with improved hearing at 15 dB air/bone gap or better. Hearing remained stable for 10 years with overall hearing of 19.2 dB air/bone gap and 50% with an air/bone gap of < or = 15 dB. In Type IV tympanoplasty, the average air/bone gap was 26 dB at 6 months, with 70% of those having improved hearing with < or = 20 dB air/bone gap. At 10 years, the overall air/bone gap was 29.3 dB, with only 28% maintaining an air/bone gap of < or = 20 dB. Poor eustachian tube function and collapse of the middle ear air space were found to be the primary causes for long-term failure. The initial hearing results using autologous bone are comparable with those achieved with synthetic prosthesis. Hearing results using autologous bone remained stable through 5 years. Beyond 5 years, Type III tympanoplasty remained stable, while there was deterioration in Type IV tympanoplasty due to poor eustachian tube function.
雕刻自体听小骨和皮质骨移植物是慢性耳科手术中最早成功用于重建听骨链的材料。在过去20年中,生物相容性植入物的使用得到了推广;因此,骨移植物已不受大多数耳科医生的青睐。为了确定自体骨移植物是否随时间保持稳定,回顾了1971年至1984年间使用自体骨移植物的115例病例。80例患者接受了III型鼓室成形术,镫骨弓存在。35例接受了IV型鼓室成形术,镫骨弓缺失。最短随访时间为2年;30例患者随访时间≥10年。在III型鼓室成形术中,总体而言,术后6个月初始气骨差距为19.7 dB,其中59%的患者听力改善至气骨差距15 dB或更小。听力在10年内保持稳定,总体气骨差距为19.2 dB,50%的患者气骨差距≤15 dB。在IV型鼓室成形术中,术后6个月平均气骨差距为26 dB,其中70%的患者听力改善至气骨差距≤20 dB。10年后,总体气骨差距为29.3 dB,只有28%的患者保持气骨差距≤20 dB。咽鼓管功能不良和中耳气腔塌陷被认为是长期失败的主要原因。使用自体骨的初始听力结果与使用合成假体的结果相当。使用自体骨的听力结果在5年内保持稳定。超过5年后,III型鼓室成形术保持稳定,而IV型鼓室成形术由于咽鼓管功能不良而恶化。