Hart R M, Filipenco V G, Kung R T
ABIOMED R&D, Inc., Danvers, Massachusetts 01923, USA.
Artif Organs. 1996 Jun;20(6):591-6.
A magnetically suspended centrifugal blood pump intended for application as a long-term implantable ventricular assist device has been built and tested. The rotor is freely suspended in the blood by magnetic and hydrostatic restoring forces. This design obviates the need for bearings and shaft seals, and eliminates the problems of reliability and thrombogenicity associated with them. The positional stability and hydrodynamic performance of the pump has been characterized in vitro at flows of up to 10 L/min at physiologic pressures. Radial position control is realized by an analog electronic feedback control system. The pressure distribution in the fluid surrounding the rotor provides dynamic control in the axial direction with no active feedback. Rotor excursion is less than 50 microns (mu) when the housing receives an impulse peaking at an acceleration of 40 g or upon sudden blockage of the flow. In vitro blood measurements indicate an acceptable level of hemolysis compared with that of a standard centrifugal pump.
一种旨在用作长期可植入式心室辅助装置的磁悬浮离心血泵已制造并进行了测试。转子通过磁力和流体静力恢复力自由悬浮在血液中。这种设计无需轴承和轴封，消除了与之相关的可靠性和血栓形成问题。该泵在生理压力下高达10升/分钟的流量下进行了体外位置稳定性和流体动力学性能表征。径向位置控制由模拟电子反馈控制系统实现。转子周围流体中的压力分布在无主动反馈的情况下提供轴向动态控制。当外壳受到加速度峰值为40g的脉冲或流量突然阻塞时，转子偏移小于50微米（μm）。体外血液测量表明，与标准离心泵相比，溶血水平可接受。
